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Travelling from Mainz to Prague by train

Looking to travel from Mainz to Prague by train? You've come to the right place!

On average, it takes around 9 hours 33 minutes to travel from Mainz to Prague by train, the fastest services can get you there in as little as 7 hours 48 minutes though. You'll usually find 31 trains per day running along the 275 miles (442 km) route between these two destinations. You’ll need to make 1 change during the journey to Prague, as there currently aren't any direct services on this route.

Plan your trip ahead and book your train tickets in advance if you want to snap up the cheapest fares. Just start a search in our Journey Planner to view the latest prices for trains from Mainz to Prague.

If you’re feeling ready to book, start looking for cheap train tickets with us today. Keep reading for more information on the journey to Prague by train, including our timetable where you can view first and last train times.

Mainz to Prague by train

First train

00:36

Last train

23:08

Departure station

Mainz

Arrival station

Prague

Journey time

From 7h 48m

Distance

275 miles (442 km)

Frequency

31 trains per day

Changes

1 change

Train and bus operators

Flixbus

FAQs about the train journey from Mainz to Prague

Want to know more about your journey from Mainz to Prague? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Mainz to Prague?

You can travel from Mainz to Prague by train in about 9 hours and 33 minutes. With around 31 trains running each day, taking the train is easy. Find out more in our Journey Planner.

How long is the train journey from Mainz to Prague?

On average, the train journey from Mainz to Prague takes around 9 hours and 33 minutes, with 31 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

What is the fastest train from Mainz to Prague?

The fastest trains from Mainz to Prague can cover the distance of 275 miles (442 km) in as little as 7 hours and 48 minutes.

Is there a direct train from Mainz to Prague?

No, you can’t travel from Mainz to Prague on a direct train, you’ll need to make at least 1 change during the journey.

Mainz to Prague train times

Check out the next trains departing from Mainz to Prague for Tuesday 6th May 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
08:1316:138h 0m, 4 changes
08:4917:228h 33m, 5 changes
09:1018:139h 3m, 2 changes
10:1018:138h 3m, 3 changes
10:1318:138h 0m, 4 changes
10:4219:228h 40m, 1 change
10:4919:228h 33m, 3 changes
11:1020:139h 3m, 2 changes
12:1020:138h 3m, 3 changes
12:1320:138h 0m, 4 changes

Cheap train tickets from Mainz to Prague

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Mainz to Prague by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

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