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Each fare is the lowest adult economy ticket fare found by our customers on Trainline. Fares booked further in advance than the dates displayed may be cheaper. Prices are updated daily, subject to change and indicative of price last update. Limited availability. Discount cards and coach journeys excluded, prices exclusive of booking fee.

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Take the train from Prague to Brussels in 11 hours

If you want to travel from Prague to Brussels by train, you've come to the right place.

You can expect the journey from Prague to Brussels by train to take around 13 hours 50 minutes. If you want to get there as quickly as possible, it can take as little as 11 hours on the fastest services. You’ll usually find around 20 trains per day running on this route, which spans 447 miles (719 km). There’s no need for any changes along the way, as there are direct trains available to Brussels. Regiojet trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Brussels.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Prague to Brussels start from £53.78 when you book in advance.

If you want to know more about the journey, keep reading for timetables, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Prague to Brussels by train

It takes an average of 13h 50m to travel from Prague to Brussels by train, over a distance of around 447 miles (719 km). There are normally 20 trains per day travelling from Prague to Brussels and tickets for this journey start from £53.78 when you book in advance.

First train

03:19

Last train

19:55

Departure station

Prague

Arrival station

Brussels

Journey time

From 11h 0m

Distance

447 miles (719 km)

Frequency

20 trains per day

Changes

Direct trains available

Price

From £53.78

Train and bus operators

European_Sleeper, Flixbus, Regiojet

FAQs about the train journey from Prague to Brussels

Want to know more about your journey from Prague to Brussels? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you travel to Brussels from Prague?

To get to Brussels from Prague, why not take the train? With 20 trains per day and an average journey time of 13 hours and 50 minutes, taking the train is a great way to travel. You can also catch the bus from Prague to Brussels. See our Journey Planner for up-to-date times and prices.

How long does it take to get from Prague to Brussels by train?

On average, it takes around 13 hours and 50 minutes to travel from Prague to Brussels by train, although you can get there in 11 hours and 0 minutes on the fastest services. With 20 trains per day running on this route, journey times may vary, so check our Journey Planner for more information.

How much is the train ticket from Prague to Brussels?

The price of a train ticket from Prague to Brussels can start from as little as £53.78, depending on the time of day, route and class you book. Train tickets may also be cheaper when you book in advance compared to buying them on the day.

How fast can trains travel from Prague to Brussels?

The fastest time a train can travel the 447 miles (719 km) from Prague to Brussels is 11 hours and 0 minutes.

Prague to Brussels train times

Check out the next trains departing from Prague to Brussels for Saturday 26th April 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesTrainDuration
03:19Praha-Holešovice15:35Bruxelles-Midieuronight 40476 Get tickets12h 16m, 2 changes
05:35Praha hl.n.17:35Bruxelles-MidiEC 362 Get tickets12h 0m, 2 changes
06:39Praha-Holešovice18:35Bruxelles-MidiEC 178 Get tickets11h 56m, 2 changes
07:35Praha hl.n.18:35Bruxelles-MidiEC 360 Get tickets11h 0m, 4 changes
07:35Praha hl.n.19:35Bruxelles-MidiEC 360 Get tickets12h 0m, 2 changes

RegioJet classes from Prague to Brussels

Compare the different travel classes offered by RegioJet when travelling from Prague to Brussels.

Onboard services on RegioJet

Discover more about the onboard services offered on trains from Prague to Brussels.

LuggageLuggageLuggage

There are no weight limits when it comes to luggage on Regiojet trains - you can take what you like, so long as you can carry it by yourself.

RestaurantRestaurantFood and drink

Choose from a wide range of drinks, snacks and light bites on board - you'll find the full menu on the Regiojet app. A free bottle of water is available for all customers. For passengers travelling with Relax or Business Class tickets, you'll also be offered a free Italian coffee or mint tea (made with real mint leaves) when on board.

WiFiWiFiEntertainment

Free WiFi is available on board. You can access the entertainment portal using the Regiojet app, or through the built-in screens on more modern Regiojet trains.

ChildPassengerChildPassengerTravel with children

Pushchairs should be folded up to be taken on board. If this isn't possible, you must store your pushchair at the front or back of the carriage.

ModeOfTransportBikeModeOfTransportBikeBikes

Bicycles cannot be transported on Regiojet trains.

PetPetPets

It's possible to bring small pets on board Regiojet trains in suitable carriers. Pets are not allowed in sleeper carriages or couchettes. Guide dogs of all sizes are permitted on board.

WheelchairWheelchairSpecial Assistance

Dedicated wheelchair spaces are available on Regiojet trains.

Cheap train tickets from Prague to Brussels

The price of train tickets from Prague to Brussels starts at £53.78 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Prague to Brussels by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

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