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About the train journey from Palermo Centrale to Sant’Ambrogio

Want to travel from Palermo Centrale to Sant’Ambrogio by train? Start your journey with us.

The train from Palermo Centrale to Sant’Ambrogio usually takes 20 hours 7 minutes on average to travel 574 miles (923 km), although the quickest services can take as little as 15 hours 11 minutes. You can expect to find 15 trains per day running on this popular route. As there aren’t any direct services running between Palermo Centrale and Sant’Ambrogio, you’ll need to make 2 changes on your way to Sant’Ambrogio.

To help you get the best train deals, we'll highlight the cheapest train ticket prices from Palermo Centrale to Sant’Ambrogio in our Journey Planner. Just remember, the sooner you book your tickets, the more you'll save!

Keep reading for more information about the train journey to Sant’Ambrogio, including FAQs, timetables with first and last train times and tips on booking cheap train tickets. If you’re ready to book, just start a search for tickets with us today.

Palermo Centrale to Sant’Ambrogio by train

First train

05:07

Last train

20:25

Departure station

Palermo Centrale

Arrival station

Sant’Ambrogio

Journey time

From 15h 11m

Distance

574 miles (923 km)

Frequency

15 trains per day

Changes

2 changes

FAQs about the train journey from Palermo Centrale to Sant’Ambrogio

Want to know more about your journey from Palermo Centrale to Sant’Ambrogio? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do you get to Sant’Ambrogio from Palermo Centrale?

To travel to Sant’Ambrogio from Palermo Centrale, you can take the train - on average, the journey takes around 20 hours and 7 minutes, though the fastest trains can take 15 hours and 11 minutes. Use our Journey Planner to get more information.

How long is the train ride from Palermo Centrale to Sant’Ambrogio?

Trains from Palermo Centrale to Sant’Ambrogio take an average of 20 hours and 7 minutes, although on the fastest services it can take just 15 hours and 11 minutes. You'll usually find 15 trains per day on this route, so use our Journey Planner to check specific dates as times may vary.

What is the quickest journey time between Palermo Centrale and Sant’Ambrogio by train?

The quickest journey time between Palermo Centrale and Sant’Ambrogio by train is 15 hours and 11 minutes.

Are there direct trains from Palermo Centrale to Sant’Ambrogio?

No, there are no direct trains running from Palermo Centrale to Sant’Ambrogio, you’ll usually need to make at least 2 changes during the journey.

Palermo Centrale to Sant’Ambrogio train times

Check out the next trains departing from Palermo Centrale to Sant’Ambrogio for Tuesday 22nd April 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
06:0504:1822h 13m, 3 changes
06:0522:1816h 13m, 3 changes
07:1304:1821h 5m, 4 changes
09:1509:1824h 3m, 2 changes
09:1507:1822h 3m, 5 changes
09:1508:1823h 3m, 4 changes
09:1509:1824h 3m, 3 changes
11:5810:1822h 20m, 2 changes
16:2011:1818h 58m, 3 changes
16:2012:1819h 58m, 2 changes

Cheap train tickets from Palermo Centrale to Sant’Ambrogio

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Palermo Centrale to Sant’Ambrogio by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

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