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Take the train from Milan to Palermo Centrale in 13 hours 15 minutes

If you want to travel from Milan to Palermo Centrale by train, you've come to the right place.

You can expect the journey from Milan to Palermo Centrale by train to take around 15 hours 55 minutes. If you want to get there as quickly as possible, it can take as little as 13 hours 15 minutes on the fastest services. You'll usually find around 18 trains per day running on this route, which spans 888 km. You'll have to make 1 change along the way on your journey to Palermo Centrale. Trenitalia trains are the main operator of services on this route, so you're likely to travel with them for all or at least part of your journey to Palermo Centrale.

Use our Journey Planner at the top of the page to search for cheap ticket prices and we'll show you how much you can save. Tickets from Milan to Palermo Centrale start from $67.20 when you book in advance.

If you want to know more about the journey, keep reading for train schedules, tips on finding cheap tickets and FAQs, including first and last train times. Want to go straight to booking? Start a search with us today!

Milan to Palermo Centrale by train

It takes an average of 15h 55m to travel from Milan to Palermo Centrale by train, over a distance of around 552 miles (888 km). There are normally 18 trains per day traveling from Milan to Palermo Centrale and tickets for this journey start from $67.20 when you book in advance.

First train

5:30 am

Last train

10:18 pm

Departure station

Milan

Arrival station

Palermo Centrale

Journey time

From 13h 15m

Distance

552 miles (888 km)

Frequency

18 trains per day

Changes

1 change

Price

From $67.20

Train and bus operators

Trenitalia, Flixbus, Autoservizi Salemi, Treni Turistici Italiani

FAQs about the train journey from Milan to Palermo Centrale

Want to know more about your journey from Milan to Palermo Centrale? We've compiled some of the most frequently asked questions by our customers to help you plan your journey.

How do I get from Milan to Palermo Centrale?

You can travel from Milan to Palermo Centrale by train in about 15 hours and 55 minutes. With around 18 trains available on this route each day, taking the train is easy. Find out more about times, tickets and prices using our Journey Planner.

How long is the train trip from Milan to Palermo Centrale?

On average, the train trip from Milan to Palermo Centrale takes around 15 hours and 55 minutes, with 18 trains per day. The duration may vary slightly depending on the specific train and any potential delays. Use our Journey Planner to check out more information.

How much is the train from Milan to Palermo Centrale?

Train tickets from Milan to Palermo Centrale start from as little as $67.20, depending on the time of booking, class of service and type of train. Booking in advance often results in better prices.

What is the fastest train from Milan to Palermo Centrale?

The fastest trains from Milan to Palermo Centrale can cover the distance of 552 miles (888 km) in as little as 13 hours and 15 minutes.

Milan to Palermo Centrale train times

Check out the next trains departing from Milan to Palermo Centrale for Tuesday May 6th 2025. For the full train timetable/schedule, or to search for a later time or date, click here.
DepartsArrivesDuration
7:50 am9:50 pm14h 0m, 2 changes
7:58 am9:50 pm13h 52m, 3 changes
8:20 am9:55 pm13h 35m, 2 changes
8:35 am9:55 pm13h 20m, 3 changes
1:30 pm6:52 am17h 22m, 2 changes
3:20 pm8:22 am17h 2m, 1 change
3:58 pm8:22 am16h 24m, 2 changes
4:05 pm8:22 am16h 17m, 2 changes
4:35 pm8:22 am15h 47m, 3 changes
7:35 pm10:01 am14h 26m, 3 changes

Trenitalia trains from Milan to Palermo Centrale

You can travel from Milan to Palermo Centrale on Trenitalia trains. When you search for times and tickets, we might also show you some other options with multiple connections or operators if they’re available.

Trenitalia is the national railway company of Italy, with a fleet including high-speed trains (Frecciarossa, Frecciargento and Frecciabianca), Intercity and Intercity night trains and regional trains. Trenitalia offers discounts and special promotions on selected routes, two types of discounted tickets for young people under 30 and people over 60.

Intercity Notte (night trains) classes from Milan to Palermo Centrale

Compare the different travel classes offered by Intercity Notte (night trains) when traveling from Milan to Palermo Centrale.

Onboard services on Intercity Notte (night trains)

Discover more about the onboard services offered on trains from Milan to Palermo Centrale.

LuggageLuggageBaggage
  • You can take your bags on board Trenitalia's Intercity Notte trains free of charge.
  • In most cases, there are no baggage size limits – you can even travel with musical instruments and sports equipment. You’ll just need to make sure that your baggage is compatible with the space available on board.
RestaurantRestaurantFood and drink

A minibar trolley service is available on all Intercity Notte trains – you can choose from a wide range of snacks and drinks. Vegan, gluten-free and lactose-free options are available too.

WiFiWiFiEntertainment

Unfortunately, free WiFi is not available on Intercity Notte trains.

ChildPassengerChildPassengerTravel with children
  • Kids under 4 can travel for free if a seat is not assigned to them. If they do have a seat, they can get 50% off Base tickets (standard fare).
  • Children aged 4-14 also get 50% off, or 30% off if they’re traveling in the Comfort couchette or Deluxe cabin Relax.
ModeOfTransportBikeModeOfTransportBikeBikes
  • You can take your folding bike with you if it’s stored in one of the dedicated luggage spaces.
  • If you have a traditional bike, you’ll need to disassemble it and place it in a bag that is not larger than 80 x 110 x 45cm (31.4 x 43.3 x 17.7 inches).
PetPetPets
  • Small pets are allowed on board free of charge, if they’re placed in a carrier or cage of max dimensions of 70 x 30 x 50cm (27.5 x 11.8 x 19.6 inches). You’ll need to buy a ticket for the whole compartment.
  • Bigger dogs are allowed on board if they have a ticket – it’s usually 50% off the Base ticket (standard fare).
WheelchairWheelchairSpecial Assistance

Intercity Notte trains have a car with designated spaces for 2 passengers with a wheelchair and 2 companions. You’ll find a wheelchair symbol outside the car.

InfoInfoOther

Depending on the class you’ll be traveling in, you’ll get to enjoy additional perks, including a wake-up service, breakfast, bedding and more.

Cheap train tickets from Milan to Palermo Centrale

The price of train tickets from Milan to Palermo Centrale starts at $67.20 one-way for a Standard Class ticket if you book in advance. Booking on the day is usually more expensive and costs can vary depending on the time of day, route or class.

Book in advance

Most of the train companies across Europe release their tickets around three to six months in advance, many of which can be cheaper the earlier you book. If you know the dates you want to travel, you may be able to find some cheaper train tickets from Milan to Palermo Centrale by booking early.§

Be flexible with your travel times

Many of the train services in Europe are also popular commuter services, lots of train companies increase ticket prices during “peak hours” (generally between 06:00 – 10:00 and 15:00 – 19:00 on weekdays). If you can, consider travelling outside of peak hours to find lower priced tickets.

Choose a slower or connecting train

On some of the busier routes, you might also have the option to take a slower or connecting train. It may take a little longer than some high-speed or direct services, but if you have a little extra time on your hands, you might find a cheaper fare. Plus, you'll have more time to enjoy the view of the countryside!

Look out for special deals

Take a look at our handy guides to find out when train operators release their special deals and offers to see if you can find cheap European train tickets for your journey.

For specific information about how to get your hands on cheap tickets, check out our European train tickets hub.

§Some train companies may not offer any Advance ticket types or cheaper deals for early bookings. On rare occasions, train companies may choose to release special offers closer to the date on last-minute or late-release tickets. This is dependent on the individual train operating company you travel with.

* Based on European average monthly visitors to Trainline’s app and website from 1.1.2023 to 10.31.2023 vs other independent retailers.

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